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edition: 1
Authors: Ryan J. Sullivan (eds.)
serie: Cancer Drug Discovery and Development 82
ISBN : 9781493921423, 9781493921430
publisher: Springer-Verlag New York
publish year: 2015
pages: 206
language: English
ebook format : PDF (It will be converted to PDF, EPUB OR AZW3 if requested by the user)
file size: 5 MB
Front Matter....Pages i-viii
Melanoma: Historical Context....Pages 1-23
Melanoma Pathogenesis....Pages 25-45
Molecular Diagnostics and Tumor Mutational Analysis....Pages 47-65
Clinical Utility of BRAF-Targeted Therapy in Melanoma....Pages 67-84
The Ethics of Randomized Trials in Oncology....Pages 85-103
Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma....Pages 105-135
Targeting the Cell Cycle and p53 in Combination with BRAF -Directed Therapy....Pages 137-162
Combination BRAF-Directed Therapy and Immunotherapy....Pages 163-182
Moving Forward: Making BRAF-Targeted Therapy Better....Pages 183-201
Back Matter....Pages 203-204