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edition: 1
Authors: Terry Kenakin (Eds.)
serie: Progress in Molecular Biology and Translational Science 115
ISBN : 9780123945877
publisher: Academic Press
publish year: 2013
pages: 471
language: English
ebook format : PDF (It will be converted to PDF, EPUB OR AZW3 if requested by the user)
file size: 7 MB
Content:
Copyright
Page iv
Contributors
Pages ix-x
Preface
Pages xi-xiii
Terry Kenakin
Chapter One - Approaches for Probing Allosteric Interactions at 7 Transmembrane Spanning Receptors
Pages 1-59
Michael T. Klein, Paige N. Vinson, Colleen M. Niswender
Chapter Two - Pharmacology of Metabotropic Glutamate Receptor Allosteric Modulators: Structural Basis and Therapeutic Potential for CNS Disorders
Pages 61-121
Karen J. Gregory, Meredith J. Noetzel, Colleen M. Niswender
Chapter Three - Mining the Potential of Label-Free Biosensors for Seven-Transmembrane Receptor Drug Discovery
Pages 123-142
Magalie Rocheville, Julio Martin, Jeff Jerman, Evi Kostenis
Chapter Four - G Protein-Coupled Receptors in Cancer: Biochemical Interactions and Drug Design
Pages 143-173
Yves Audigier, François-Xavier Picault, Carline Chaves-Almagro, Bernard Masri
Chapter Five - GPCRs in Stem Cell Function
Pages 175-216
Van A. Doze, Dianne M. Perez
Chapter Six - Application of Receptor Theory to Allosteric Modulation of Receptors
Pages 217-290
David A. Hall
Chapter Seven - What Ligand-Gated Ion Channels Can Tell Us About the Allosteric Regulation of G Protein-Coupled Receptors
Pages 291-347
Frederick J. Ehlert
Chapter Eight - Modeling Cooperativity Effects in Dimeric G Protein-Coupled Receptors
Pages 349-373
JesГєs Giraldo
Chapter Nine - Chemokine Receptor Oligomerization and Allostery
Pages 375-420
Bryan Stephens, Tracy M. Handel
Chapter Ten - Fine-Tuning of GPCR Signals by Intracellular G Protein Modulators
Pages 421-453
Peishen Zhao, Wendy Cladman, Hubert H.M. Van Tol, Peter Chidiac
Index
Pages 455-471
